Publication

2020

Functional evaluation of the C-terminal region of bacteriophage T4 Rad50. 2020 HE Streff, Y Gao, SW Nelson. Biochem Biophys Res Commun 526, 485-90

2019

Different mechanisms for translocation by monomeric and hexameric helicases. 2019 Y Gao#, W Yang#. Current Opinion in Structural Biology 61, 25-32 (# Co-corresponding)

Replisome structure suggests mechanism for continuous fork progression and post-replication repair. 2019 W Yang, MM Seidman, WD Rupp, Y Gao. DNA repair, 102658

Structures and operating principles of the replisome. 2019 Y Gao, Y Cui, T Fox, S Lin, H Wang, N de Val, ZH Zhou, W Yang. Science 363 (6429), eaav7003

2016-2018

Bypassing a 8, 5′-cyclo-2′-deoxyadenosine lesion by human DNA polymerase η at atomic resolution. 2018 PJ Weng*, Y Gao*, MT Gregory, P Wang, Y Wang, W Yang. Proceedings of the National Academy of Sciences 115 (42), 10660-10665 (* Equal contribution)

Translesion and repair DNA polymerases: Diverse structure and mechanism. 2018 W Yang, Y Gao. Annual Review of Biochemistry 87, 239-261

A new paradigm of DNA synthesis: three-metal-ion catalysis. 2017 W Yang, PJ Weng, Y Gao. Cell and Bioscience 7

Detection of reaction intermediates in Mg2+-dependent DNA synthesis and RNA degradation by time-resolved X-ray crystallography. 2017 NL Samara*, Y Gao*, J Wu, W Yang. Methods in Enzymology 592, 283-327 (* Equal contribution)

A network of allosterically coupled residues in the bacteriophage T4 Mre11–Rad50 complex. 2016 Y Gao*, JR Meyer*, SW Nelson. Protein Science 25 (11), 2054-2065 (* Equal contribution)

Capture of a third Mg2+ is essential for catalyzing DNA synthesis. 2016 Y Gao, W Yang. Science 352 (6291), 1334

2010-2015

Functional analysis of the bacteriophage T4 Rad50 homolog (gp46) coiled-coil domain. 2015 T Barfoot, TJ Herdendorf, BR Behning, BA Stohr, Y Gao, KN Kreuzer, SW Nelson. Journal of Biological Chemistry 290 (39), 23905-23915

How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis. 2015 YS Lee, Y Gao, Y Wei. NATURE STRUCTURAL & MOLECULAR BIOLOGY 22, 298–303

Autoinhibition of bacteriophage T4 Mre11 by its C-terminal domain. 2014 Y Gao, SW Nelson. Journal of Biological Chemistry 289 (38), 26505-26513

Central cavity of fructose-1, 6-bisphosphatase and the evolution of AMP/fructose 2, 6-bisphosphate synergism in eukaryotic organisms. 2014 Y Gao, L Shen, RB Honzatko. Journal of Biological Chemistry 289 (12), 8450-8461

Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1, 6-bisphosphatase. 2013 Y Gao, CV Iancu, S Mukind, JY Choe, RB Honzatko. Biochemistry 52 (31), 5206-5216

Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis. 2012 K Zhou, Y Gao, JA Hoy, FM Mann, RB Honzatko, RJ Peters. Journal of Biological Chemistry 287 (9), 6840-6850

Terpenoid synthase structures: a so far incomplete view of complex catalysis. 2012 Y Gao, RB Honzatko, RJ Peters. Natural product reports 29 (10), 1153-1175

Crystallization and preliminary crystallographic analysis of tRNA (m7G46) methyltransferase from Escherichia coli. Q Liu, Y Gao, W Yang, H Zhou, X Zhang, M Teng, L Niu. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 64 (8), 743-745